The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles

Tissue factor (TF) is critical for the activation of blood coagulation. TF function is regulated by the amount of externalised phosphatidylserine (PS) and phosphatidylethanolamine (PE) on the surface of the cell in which it is expressed. We investigated the role PS and PE in fibroblast TF function....

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Veröffentlicht in:PLoS One
Hauptverfasser: Rosas, Marcela, Slatter, David A., Obaji, Samya G., Webber, Jason P., Alvarez-Jarreta, Jorge, Thomas, Christopher P., Aldrovandi, Maceler, Tyrrell, Victoria J., Jenkins, Peter V., O’Donnell, Valerie B., Collins, Peter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544082/
https://ncbi.nlm.nih.gov/pubmed/33031441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240189
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