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Adaptive immunity selects against malaria infection blocking mutations
The mutation responsible for Duffy negativity, which impedes Plasmodium vivax infection, has reached high frequencies in certain human populations. Conversely, mutations capable of blocking the more lethal P. falciparum have not succeeded in malarious zones. Here we present an evolutionary-epidemiol...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544067/ https://ncbi.nlm.nih.gov/pubmed/33031369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008181 |
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