Centella asiatica Water Extract Shows Low Potential for Cytochrome P450–Mediated Drug Interactions

Centella asiatica (CA) shows considerable promise for development as a botanical drug for cognitive decline. Its primary bioactive components include triterpene glycosides asiaticoside and madecassoside and their corresponding aglycones asiatic acid and madecassic acid. Exploration of the bioactivit...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Wright, Kirsten M., Magana, Armando Alcazar, Laethem, Ronald M., Moseley, Caroline L., Banks, Troy T., Maier, Claudia S., Stevens, Jan F., Quinn, Joseph F., Soumyanath, Amala
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Special Section on Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543484/
https://ncbi.nlm.nih.gov/pubmed/32581050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.090860
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