Intestinal Receptor of SARS-CoV-2 in Inflamed IBD Tissue Seems Downregulated by HNF4A in Ileum and Upregulated by Interferon Regulating Factors in Colon

BACKGROUND: Patients with inflammatory bowel disease [IBD] are considered immunosuppressed, but do not seem more vulnerable for COVID-19. Nevertheless, intestinal inflammation has shown to be an important risk factor for SARS-CoV-2 infection and prognosis. Therefore, we investigated the role of inte...

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Dettagli Bibliografici
Pubblicato in:J Crohns Colitis
Autori principali: Verstockt, Bram, Verstockt, Sare, Abdu Rahiman, Saeed, Ke, Bo-jun, Arnauts, Kaline, Cleynen, Isabelle, Sabino, João, Ferrante, Marc, Matteoli, Gianluca, Vermeire, Séverine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543339/
https://ncbi.nlm.nih.gov/pubmed/32915959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjaa185
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