Treatment of COVID-19 Patients with Prolonged Post-Symptomatic Viral Shedding with Leflunomide -- a Single-Center, Randomized, Controlled Clinical Trial

OBJECTIVE: To evaluate the efficacy and safety of leflunomide, an approved dihydroorotate dehydrogenase inhibitor, to treat COVID-19 patients with prolonged post-symptomatic viral shedding. METHODS: We conducted a prospective, randomized, controlled, open-label trial involving hospitalized adult COV...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Wang, Mengmei, Zhao, Yang, Hu, Weihua, Zhao, Dong, Zhang, Yunting, Wang, Tao, Zheng, Zhishui, Li, Xiaochen, Zeng, Shaolin, Liu, Zhenlian, Lu, Li, Wan, Zhihui, Hu, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543328/
https://ncbi.nlm.nih.gov/pubmed/32955081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciaa1417
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