Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas

BACKGROUND: The mitogen-activated protein kinases/extracelluar signal-regulated kinases pathway is involved in cell growth and proliferation, and mutations in BRAF have made it an oncogene of interest in pediatric cancer. Previous studies found that BRAF mutations as well as KIAA1549–BRAF fusions ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Grob, Sydney T, Nobre, Liana, Campbell, Kristen R, Davies, Kurtis D, Ryall, Scott, Aisner, Dara L, Hoffman, Lindsey, Zahedi, Shadi, Morin, Andrew, Crespo, Michele, Nellan, Anandani, Green, Adam L, Foreman, Nicholas, Vibhakar, Rajeev, Hankinson, Todd C, Handler, Michael H, Hawkins, Cynthia, Tabori, Uri, Kleinschmidt-DeMasters, B K, Mulcahy Levy, Jean M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542983/
https://ncbi.nlm.nih.gov/pubmed/33063010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa103
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