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Creation of Golden Gate constructs for gene doctoring

BACKGROUND: Gene doctoring is an efficient recombination-based genetic engineering approach to mutagenesis of the bacterial chromosome that combines the λ-Red recombination system with a suicide donor plasmid that is cleaved in vivo to generate linear DNA fragments suitable for recombination. The us...

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Bibliographic Details
Published in:BMC Biotechnol
Main Authors: Thomson, Nicholas M., Zhang, Chuanzhen, Trampari, Eleftheria, Pallen, Mark J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542709/
https://ncbi.nlm.nih.gov/pubmed/33028286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-020-00648-5
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