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Chromodomain Helicase DNA-Binding Protein 5 Inhibits Renal Cell Carcinoma Tumorigenesis by Activation of the p53 and RB Pathways

Chromodomain helicase DNA-binding protein 5 (CHD5) plays a crucial tumor suppressor role in multiple types of tumors. For this study, we investigated its clinical significance and the molecular mechanism(s) underlying tumorigenesis in renal cell carcinoma (RCC). Initially, CHD5 expression was assess...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Huang, Sheng, Yan, Qitao, Xiong, Shilin, Peng, Yiqi, Zhao, Rui, Liu, Chunxiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542531/
https://ncbi.nlm.nih.gov/pubmed/33062682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5425612
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