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Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome
Marfan syndrome (MFS) is a systemic disorder of connective tissue caused by pathogenic variants in the fibrillin-1 (FBN1) gene. Myocardial dysfunction has been demonstrated in MFS patients and mouse models, but little is known about the intrinsic effect on the cardiomyocytes (CMs). In this study, bo...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7542175/ https://ncbi.nlm.nih.gov/pubmed/33028885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73802-w |
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