Quantitative evaluation of hepatic integrin α(v)β(3) expression by positron emission tomography imaging using (18)F-FPP-RGD(2) in rats with non-alcoholic steatohepatitis

BACKGROUND: Integrin α(v)β(3), which are expressed by activated hepatic stellate cells in non-alcoholic steatohepatitis (NASH), play an important role in the fibrosis. Recently, we reported that an RGD peptide positron emission tomography (PET) probe is useful as a predictor of hepatic fibrosis. Kin...

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Vydáno v:EJNMMI Res
Hlavní autoři: Hiroyama, Shuichi, Rokugawa, Takemi, Ito, Miwa, Iimori, Hitoshi, Morita, Ippei, Maeda, Hiroki, Fujisawa, Kae, Matsunaga, Keiko, Shimosegawa, Eku, Abe, Kohji
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541810/
https://ncbi.nlm.nih.gov/pubmed/33026561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00704-3
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