Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2

IgE antibodies drive the symptoms of allergic disease upon crosslinking allergens on mast cells or basophils. If the IgE binding sites on the allergens could be identified, it may be useful for creating new forms of immunotherapy. However, direct knowledge of the human IgE epitopes is limited due to...

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Udgivet i:J Immunol
Main Authors: Mueller, Geoffrey A., Glesner, Jill, Daniel, Jacob L., Zhang, Jian, Hyduke, Noah, Richardson, Crystal M., DeRose, Eugene F., Chapman, Martin D., Peebles, R. Stokes, Smith, Scott A., Pomés, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541722/
https://ncbi.nlm.nih.gov/pubmed/32907999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000295
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