Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer’s pathology

INTRODUCTION: Abnormal gene expression patterns may contribute to the onset and progression of late-onset Alzheimer’s disease (LOAD). METHODS: We performed transcriptome-wide meta-analysis (N=1,440) of blood-based microarray gene expression profiles as well as neuroimaging and CSF endophenotype anal...

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Veröffentlicht in:Alzheimers Dement
Hauptverfasser: Nho, Kwangsik, Nudelman, Kelly, Allen, Mariet, Hodges, Angela, Kim, Sungeun, Risacher, Shannon L., Apostolova, Liana, Lin, Kuang, Lunnon, Katie, Wang, Xue, Burgess, Jeremy D., Ertekin-Taner, Nilüfer, Petersen, Ronald C., Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac, Patel, Vishal, Foroud, Tatiana, Faber, Kelley M., Lovestone, Simon, Simmons, Andrew, Weiner, Michael W., Saykin, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541709/
https://ncbi.nlm.nih.gov/pubmed/32755048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12092
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