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Acrylamide alters CREB and retinoic acid signalling pathways during differentiation of the human neuroblastoma SH-SY5Y cell line

Acrylamide (ACR) is a known neurotoxicant which crosses the blood–brain barrier, passes the placenta and has been detected in breast milk. Hence, early-life exposure to ACR could lead to developmental neurotoxicity. The aim of this study was to elucidate if non-cytotoxic concentrations of ACR alter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Attoff, Kristina, Johansson, Ylva, Cediel-Ulloa, Andrea, Lundqvist, Jessica, Gupta, Rajinder, Caiment, Florian, Gliga, Anda, Forsby, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541504/
https://ncbi.nlm.nih.gov/pubmed/33028897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73698-6
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