A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida

Fluorine is a key element in the synthesis of molecules broadly used in medicine, agriculture and materials. Addition of fluorine to organic structures represents a unique strategy for tuning molecular properties, yet this atom is rarely found in Nature and approaches to integrate fluorometabolites...

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Udgivet i:Nat Commun
Main Authors: Calero, Patricia, Volke, Daniel C., Lowe, Phillip T., Gotfredsen, Charlotte H., O’Hagan, David, Nikel, Pablo I.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541441/
https://ncbi.nlm.nih.gov/pubmed/33028813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18813-x
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