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PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells

The signalling protein PKCγ is a major regulator of Purkinje cell development and synaptic function. We have shown previously that increased PKCγ activity impairs dendritic development of cerebellar Purkinje cells. Mutations in the protein kinase Cγ gene (PRKCG) cause spinocerebellar ataxia type 14...

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Publicat a:Mol Neurobiol
Autors principals: Winkler, Sabine C., Shimobayashi, Etsuko, Kapfhammer, Josef P.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541385/
https://ncbi.nlm.nih.gov/pubmed/32860158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02038-6
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