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Axonal Protection by Nicotinamide Riboside via SIRT1-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration

Nicotinamide adenine dinucleotide (NAD(+)) synthesis pathway has been involved in many biological functions. Nicotinamide riboside (NR) is widely used as an NAD(+) precursor and known to increase NAD(+) level in several tissues. The present study aimed to examine the effect of NR on tumor necrosis f...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Kitaoka, Yasushi, Sase, Kana, Tsukahara, Chihiro, Fujita, Naoki, Arizono, Ibuki, Takagi, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541376/
https://ncbi.nlm.nih.gov/pubmed/32820458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02063-5
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