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Impact of data preprocessing on cell-type clustering based on single-cell RNA-seq data

BACKGROUND: Advances in single-cell RNA-seq technology have led to great opportunities for the quantitative characterization of cell types, and many clustering algorithms have been developed based on single-cell gene expression. However, we found that different data preprocessing methods show quite...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wang, Chunxiang, Gao, Xin, Liu, Juntao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541255/
https://ncbi.nlm.nih.gov/pubmed/33028196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03797-8
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