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Evaluation of soluble expression of recombinant granulocyte macrophage stimulating factor (rGM-CSF) by three different E. coli strains

BACKGROUND AND PURPOSE: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine with a wide range of therapeutic applications although expression of GM-CSF in Escherichia coli (E. coli) usually leads to formation of insoluble aggregates mostly lack biological activity. The aim of thi...

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Publicat a:Res Pharm Sci
Autors principals: Soheili, Sina, Jahanian-Najafabadi, Ali, Akbari, Vajihe
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer - Medknow 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540813/
https://ncbi.nlm.nih.gov/pubmed/33088322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.288424
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