Formulation of the prefusion RSV F protein with a Th1/Th2-balanced adjuvant provides complete protection without Th2-skewed immunity in RSV-experienced young mice

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections among infants with most infections occurring in the first year of life. Multiple RSV exposures are required for children to mount adult-like immune responses. Although adult RSV immunity is associated with les...

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Bibliografische gegevens
Gepubliceerd in:Vaccine
Hoofdauteurs: Kosanovich, Jessica L., Eichinger, Katherine M., Lipp, Madeline A., Yondola, Mark A., Perkins, Timothy N., Empey, Kerry M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540734/
https://ncbi.nlm.nih.gov/pubmed/32829976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.08.023
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