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Minimal deuterium isotope effects in quantitation of dimethyl‐labeled complex proteomes analyzed with capillary zone electrophoresis/mass spectrometry

Stable heavy‐isotope labeling is commonly used in quantitative proteomics. Several common techniques incorporate deuterium ((2)H) as the heavy isotopic label using reductive amination with formaldehyde. Compared with alternatives, dimethyl labeling reagents are inexpensive and the labeling chemistry...

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Bibliografiset tiedot
Julkaisussa:Electrophoresis
Päätekijät: Yan, Xiaojing, Sun, Liangliang, Dovichi, Norman J., Champion, Matthew M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540333/
https://ncbi.nlm.nih.gov/pubmed/32548848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.202000051
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