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Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation

Aims: The aim of the present study was to investigate the effects of astragaloside IV (As-IV) on mechanical stress-induced myocardial hypertrophy, with a focus on autophagy and inflammation. Methods: A rat cardiac hypertrophy model was established by narrowing the abdominal aorta, and a cell hypertr...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Zhang, Tong, Wang, Hongxin, Lu, Meili, Zhao, Kun, Yin, Jiawei, Liu, Yang, Sun, Yang
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540164/
https://ncbi.nlm.nih.gov/pubmed/33042423
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