Exosomes released by human umbilical cord mesenchymal stem cells protect against renal interstitial fibrosis through ROS-mediated P38MAPK/ERK signaling pathway

Mesenchymal stem cells (MSCs) and their conditioned medium attenuate renal fibrosis in an irreversible model of unilateral ureteral obstruction (UUO). However, the key components that play a role in the paracrine effects of MSCs and their mechanisms of action are not well understood. Therefore, in t...

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Dettagli Bibliografici
Pubblicato in:Am J Transl Res
Autori principali: Liu, Bo, Hu, Dong, Zhou, Yu, Yu, Yihang, Shen, Lianju, Long, Chunlan, Butnaru, Denis, Timashev, Peter, He, Dawei, Lin, Tao, Xu, Tao, Zhang, Deying, Wei, Guanghui
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540090/
https://ncbi.nlm.nih.gov/pubmed/33042402
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