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Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19

Since the first case reports in Wuhan, China, the SARS-CoV-2 has caused a pandemic and took lives of > 8,35,000 people globally. This single-stranded RNA virus uses Angiotensin-converting enzyme 2 (ACE2) as a receptor for entry into the host cell. Overexpression of ACE2 is mainly observed in hype...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biochem
Autori principali: Kumar, Pravindra, Sah, Ashok Kumar, Tripathi, Greesham, Kashyap, Anjali, Tripathi, Avantika, Rao, Rashmi, Mishra, Prabhu C., Mallick, Koustav, Husain, Amjad, Kashyap, Manoj Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539757/
https://ncbi.nlm.nih.gov/pubmed/33029696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-020-03924-2
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