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Glioma Cells With Genetically Engineered IGF-I Receptor Downregulation Can Persist in the Brain in a Dormant State

Glioblastoma multiforme is an aggressive malignancy, resistant to standard treatment modalities and associated with poor prognosis. We analyzed the role of the IGF system in intracerebral glioma growth using human and rat glioma cells. The glioma cells C6 and U87MG were transduced with a genetically...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Samani, Amir A., Nalbantoglu, Josephine, Brodt, Pnina
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539665/
https://ncbi.nlm.nih.gov/pubmed/33072581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.555945
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