Design and Development of (99m)Tc-Labeled FAPI Tracers for SPECT Imaging and (188)Re Therapy

Most epithelial tumors recruit fibroblasts and other nonmalignant cells and activate them into cancer-associated fibroblasts. This often leads to overexpression of the membrane serine protease fibroblast-activating protein (FAP). It has already been shown that DOTA-bearing FAP inhibitors (FAPIs) gen...

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Vydáno v:J Nucl Med
Hlavní autoři: Lindner, Thomas, Altmann, Annette, Krämer, Susanne, Kleist, Christian, Loktev, Anastasia, Kratochwil, Clemens, Giesel, Frederik, Mier, Walter, Marme, Frederik, Debus, Jürgen, Haberkorn, Uwe
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Nuclear Medicine 2020
Témata:
Theranostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539653/
https://ncbi.nlm.nih.gov/pubmed/32169911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.239731
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