Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8

BACKGROUND: To determine safety and efficacy of single cycle induction treatment with cisplatin/docetaxel and durvalumab/tremelimumab in stage III-IVB head and neck cancer. METHODS: Patients received a single cycle of cisplatin 30 mg/m² on days 1–3 and docetaxel 75 mg/m² on day 1 combined with durva...

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發表在:J Immunother Cancer
Main Authors: Hecht, Markus, Gostian, Antoniu Oreste, Eckstein, Markus, Rutzner, Sandra, von der Grün, Jens, Illmer, Thomas, Hautmann, Matthias G, Klautke, Gunther, Laban, Simon, Brunner, Thomas, Hinke, Axel, Becker, Ina, Frey, Benjamin, Semrau, Sabine, Geppert, Carol I, Hartmann, Arndt, Balermpas, Panagiotis, Budach, Wilfried, Gaipl, Udo S, Iro, Heinrich, Fietkau, Rainer
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2020
主題:
Clinical/Translational Cancer Immunotherapy
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539609/
https://ncbi.nlm.nih.gov/pubmed/33023982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001378
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