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Ablation of Fam20c causes amelogenesis imperfecta via inhibiting Smad dependent BMP signaling pathway

BACKGROUND: Amelogenesis imperfecta (AI) is a type of hereditary diseases that manifest defects in the formation or mineralization of enamel. Recently, it is reported that inactivation of FAM20C, a well-known Golgi casein kinase, caused AI. However, the mechanism of it is still unknown. The aim of t...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Liu, Jing, Saiyin, Wuliji, Xie, Xiaohua, Mao, Limin, Li, Lili
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539414/
https://ncbi.nlm.nih.gov/pubmed/33028367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-020-00270-7
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