CYP1A1 and Cnr nitroreductase bioactivated niclosamide in vitro

Niclosamide produces genotoxic effects, such as point mutations in Salmonella sp., sperm-head abnormalities in mice and clastogenic effects in human lymphocytes in vitro and in vivo. As cytochrome P450 could be involved in the bioactivation of niclosamide, we investigated which subfamily was involve...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mutagenesis
Asıl Yazarlar: Beristain-Castillo, Evelyn, Martínez-Vázquez, Mariano, Camacho-Carranza, Rafael, Espinosa-Aguirre, Javier J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Original Manuscript
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539354/
https://ncbi.nlm.nih.gov/pubmed/23956140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/get043
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