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Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity

The polymorphic drug-metabolizing enzyme CYP2D6, which is responsible for the metabolism of most psychoactive compounds, is expressed not only in the liver, but also in the brain. The effects of its marked genetic polymorphism on the individual capacity to metabolize drugs are well known, but its ro...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Viviani, Roberto, Messina, Irene, Bosch, Julia E., Dommes, Lisa, Paul, Anna, Schneider, Katharina L., Scholl, Catharina, Stingl, Julia C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539151/
https://ncbi.nlm.nih.gov/pubmed/33024081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01020-z
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