HMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes

Previously, we found that mevalonic acid stimulates 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR) expression in bovine intramuscular adipocytes to influence adipocyte differentiation. However, any direct links among HMGR, steroidogenic genes, and cholesterol content remain unclear. RNA-Seq...

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Udgivet i:Sci Rep
Main Authors: Lin, Haichao, Wei, Chen, Zhang, Xianglun, You, Wei, Jin, Qing, Tan, Xiuwen, Zhao, Hongbo, Zhang, Chen, Liu, Xiaomu, Liu, Guifen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538946/
https://ncbi.nlm.nih.gov/pubmed/33024216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73626-8
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