Anti-IL-6 Versus Anti-IL-6R Blocking Antibodies to Treat Acute Ebola Infection in BALB/c Mice: Potential Implications for Treating Cytokine Release Syndrome

Cytokine release syndrome (CRS) is known to be a factor in morbidity and mortality associated with acute viral infections including those caused by filoviruses and coronaviruses. IL-6 has been implicated as a cytokine negatively associated with survival after filovirus and coronavirus infection. How...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Rubsamen, Reid, Burkholz, Scott, Massey, Christopher, Brasel, Trevor, Hodge, Tom, Wang, Lu, Herst, Charles, Carback, Richard, Harris, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538647/
https://ncbi.nlm.nih.gov/pubmed/33071786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.574703
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