M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer

Tumor associated macrophages (TAMs) play a critical role in biology of various cancers, including breast cancer. In the current study, we defined “M1” macrophage and “M1”/“M2” ratio by transcriptomic signatures using xCell. We investigated the association between high level of “M1” macrophage or “M1...

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Pubblicato in:Sci Rep
Autori principali: Oshi, Masanori, Tokumaru, Yoshihisa, Asaoka, Mariko, Yan, Li, Satyananda, Vikas, Matsuyama, Ryusei, Matsuhashi, Nobuhisa, Futamura, Manabu, Ishikawa, Takashi, Yoshida, Kazuhiro, Endo, Itaru, Takabe, Kazuaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538579/
https://ncbi.nlm.nih.gov/pubmed/33024179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73624-w
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