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Emulating a target trial of statin use and risk of dementia using cohort data

OBJECTIVE: Observational data can be used to attempt to emulate a target trial of statin use and estimate analogues of intention-to-treat and per protocol effects on dementia risk. METHODS: Using data from a prospective cohort study in the Netherlands, we conceptualized a sequence of “trials” in whi...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Caniglia, Ellen C., Rojas-Saunero, L. Paloma, Hilal, Saima, Licher, Silvan, Logan, Roger, Stricker, Bruno, Ikram, M. Arfan, Swanson, Sonja A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538212/
https://ncbi.nlm.nih.gov/pubmed/32753444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000010433
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