Can endolysosomal deacidification and inhibition of autophagy prevent severe COVID-19?

The possibility is examined that immunomodulatory pharmacotherapy may be clinically useful in managing the pandemic coronavirus disease 2019 (COVID-19), known to result from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive-sense single-stranded RNA virus. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Life Sci
Prif Awduron: Morris, Gerwyn, Athan, Eugene, Walder, Ken, Bortolasci, Chiara C., O'Neil, Adrienne, Marx, Wolf, Berk, Michael, Carvalho, André F., Maes, Michael, Puri, Basant K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Inc. 2020
Pynciau:
Review Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537668/
https://ncbi.nlm.nih.gov/pubmed/33035581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2020.118541
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