Profiling HPV-16–specific T cell responses reveals broad antigen reactivities in oropharyngeal cancer patients

Cellular immunotherapeutics targeting the human papillomavirus (HPV)–16 E6 and E7 proteins have achieved limited success in HPV-positive oropharyngeal cancer (OPC). Here we have conducted proteome-wide profiling of HPV-16–specific T cell responses in a cohort of 66 patients with HPV-associated OPC a...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Bhatt, Kunal H., Neller, Michelle A., Srihari, Sriganesh, Crooks, Pauline, Lekieffre, Lea, Aftab, Blake T., Liu, Howard, Smith, Corey, Kenny, Liz, Porceddu, Sandro, Khanna, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537390/
https://ncbi.nlm.nih.gov/pubmed/32716518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200389
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