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Improving precision and power in randomized trials for COVID‐19 treatments using covariate adjustment, for binary, ordinal, and time‐to‐event outcomes

Time is of the essence in evaluating potential drugs and biologics for the treatment and prevention of COVID‐19. There are currently 876 randomized clinical trials (phase 2 and 3) of treatments for COVID‐19 registered on clinicaltrials.gov. Covariate adjustment is a statistical analysis method with...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Benkeser, David, Díaz, Iván, Luedtke, Alex, Segal, Jodi, Scharfstein, Daniel, Rosenblum, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7537316/
https://ncbi.nlm.nih.gov/pubmed/32978962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13377
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