A dCas9-Based System Identifies a Central Role for Ctf19 in Kinetochore-Derived Suppression of Meiotic Recombination

In meiosis, crossover (CO) formation between homologous chromosomes is essential for faithful segregation. However, misplaced meiotic recombination can have catastrophic consequences on genome stability. Within pericentromeres, COs are associated with meiotic chromosome missegregation. In organisms...

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Publicat a:Genetics
Autors principals: Kuhl, Lisa-Marie, Makrantoni, Vasso, Recknagel, Sarah, Vaze, Animish N., Marston, Adele L., Vader, Gerben
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2020
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536843/
https://ncbi.nlm.nih.gov/pubmed/32843356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303384
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