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Genome-wide Study Identifies Association between HLA-B(∗)55:01 and Self-Reported Penicillin Allergy

Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscoring a need for understanding their underlying mechanisms and risk factors. The extent to which germline genetic variation influences the risk of commonly reported drug allergies such as penicillin aller...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Krebs, Kristi, Bovijn, Jonas, Zheng, Neil, Lepamets, Maarja, Censin, Jenny C., Jürgenson, Tuuli, Särg, Dage, Abner, Erik, Laisk, Triin, Luo, Yang, Skotte, Line, Geller, Frank, Feenstra, Bjarke, Wang, Wei, Auton, Adam, Raychaudhuri, Soumya, Esko, Tõnu, Metspalu, Andres, Laur, Sven, Roden, Dan M., Wei, Wei-Qi, Holmes, Michael V., Lindgren, Cecilia M., Phillips, Elizabeth J., Mägi, Reedik, Milani, Lili, Fadista, João
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536643/
https://ncbi.nlm.nih.gov/pubmed/32888428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.08.008
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