Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms

Natural products have been recognized as important bioactive compounds on the basis of their wide biological properties. Here we investigated the antitumor effect and molecular mechanisms of the diterpene Fruticuline A (fruti) from Salvia lachnostachys, in human cancer cell lineages and Solid Ehrlic...

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Vydáno v:Sci Rep
Hlavní autoři: Corso, Claudia Rita, Stipp, Maria Carolina, Radulski, Débora Rasec, Mariott, Marihá, da Silva, Luisa Mota, de Souza Ramos, Edneia Amancio, Klassen, Giseli, Queiroz Telles, José Ederaldo, Oliveira, Cristhian Santos, Stefanello, Maria Élida Alves, Verhoeven, Arthur J., Oude Elferink, Ronald P. J., Acco, Alexandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536426/
https://ncbi.nlm.nih.gov/pubmed/33020521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73432-2
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