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Residues 315 and 369 in HN Protein Contribute to the Thermostability of Newcastle Disease Virus

Thermostable Newcastle disease virus (NDV) vaccines have been widely used in areas where a “cold-chain” is not reliable. However, the molecular mechanism of NDV thermostability remains poorly understood. In this work, we constructed chimeric viruses by exchanging viral fusion (F) and/or hemagglutini...

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Publicat a:Front Microbiol
Autors principals: Ruan, Baoyang, Zhang, Xiaorong, Zhang, Chengcheng, Du, Pengyu, Meng, Chengcheng, Guo, Mengjiao, Wu, Yantao, Cao, Yongzhong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536312/
https://ncbi.nlm.nih.gov/pubmed/33072019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.560482
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