Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism

Despite the discovery of the tubercle bacillus more than 130 years ago, its physiology and the mechanisms of virulence are still not fully understood. A comprehensive analysis of the proteomes of members of the human-adapted Mycobacterium tuberculosis complex (MTBC) lineages 3, 4, 5, and 7 was condu...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yimer, Solomon Abebe, Kalayou, Shewit, Homberset, Håvard, Birhanu, Alemayehu Godana, Riaz, Tahira, Zegeye, Ephrem Debebe, Lutter, Timo, Abebe, Markos, Holm-Hansen, Carol, Aseffa, Abraham, Tønjum, Tone
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7536270/
https://ncbi.nlm.nih.gov/pubmed/33072011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.550760
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