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Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation

Fanconi anemia (FA) is a chromosome instability syndrome of children caused by inherited mutations in one of FA genes, which together constitute a DNA interstrand cross-link (ICL) repair, or the FA pathway. Monoubiquitination of Fanconi anemia group D2 protein (FANCD2) by the multisubunit ubiquitin...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Nagareddy, Bhavika, Khan, Arafat, Kim, Hyungjin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535921/
https://ncbi.nlm.nih.gov/pubmed/32763975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015288
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