5PSQ-081 Determination of genetic polymorphisms in tpmt and nudt-15 in the paediatric onco-haematologic patient. preliminary results

BACKGROUND: Genetic-polymorphisms in thiopurine-methyltransferase (TPMT) and Nudix-hydrolase15 (NUDT15) have been related to higher risk of toxicity associated with administration of 6-mercaptopurine(6-MP). PURPOSE: To describe the implementation of polymorphisms determination in TPMT and NUDT15 in...

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Detalhes bibliográficos
Publicado no:Eur J Hosp Pharm
Main Authors: Gil, S García, Díaz, R Ramos, Cruz, M González, Romero, MM Viña, Casariego, GJ Nazco, Méndez, H González, Rojas, S Hernández, Sánchez, P Yanes, Nicolás, F Gutiérrez
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2018
Assuntos:
Section 5: Patient safety and quality assurance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535810/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ejhpharm-2018-eahpconf.435
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