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4CPS-071 Therapeutic drug monitoring and safety of high-dose amikacin in critically ill patients

BACKGROUND: Pharmacokinetic parameters are altered in critically ill patients, such as an increase in volume of distribution of hydrophillic drugs. Peak plasma levels of amikacin, a concentration-dependent antibiotic, could be reduced in critically ill patients. Therefore, current recommendations in...

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Detalhes bibliográficos
Publicado no:Eur J Hosp Pharm
Main Authors: Barcelo, J, Fernández-Sala, X, Marin-Casino, M, Grau, S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535322/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ejhpharm-2018-eahpconf.162
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