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Molecular docking between human TMPRSS2 and SARS-CoV-2 spike protein: conformation and intermolecular interactions

Entry of SARS-CoV-2, etiological agent of COVID-19, in the host cell is driven by the interaction of its spike protein with human ACE2 receptor and a serine protease, TMPRSS2. Although complex between SARS-CoV-2 spike protein and ACE2 has been structurally resolved, the molecular details of the SARS...

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Détails bibliographiques
Publié dans:AIMS Microbiol
Auteurs principaux: Hussain, Mushtaq, Jabeen, Nusrat, Amanullah, Anusha, Baig, Ayesha Ashraf, Aziz, Basma, Shabbir, Sanya, Raza, Fozia, Uddin, Nasir
Format: Artigo
Langue:Inglês
Publié: AIMS Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535071/
https://ncbi.nlm.nih.gov/pubmed/33029570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/microbiol.2020021
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