Mechanisms and therapeutic implications of RTA 408, an activator of Nrf2, in subarachnoid hemorrhage–induced delayed cerebral vasospasm and secondary brain injury

OBJECTIVES: More and more evidence suggests oxidative stress and inflammation contribute importantly to subarachnoid hemorrhage (SAH)-induced cerebral vasospasm and secondary brain injury. Recent evidence indicates Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) increases the expression of antiox...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tsai, Tai-Hsin, Lin, Szu-Huai, Wu, Chieh-Hsin, Tsai, Yi-Cheng, Yang, Sheau-Fang, Lin, Chih-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535038/
https://ncbi.nlm.nih.gov/pubmed/33017422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240122
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