A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster

Mutations in the gene encoding the ubiquitously expressed RNA-binding protein ZC3H14 result in a non-syndromic form of autosomal recessive intellectual disability in humans. Studies in Drosophila have defined roles for the ZC3H14 ortholog, Nab2 (aka Drosophila Nab2 or dNab2), in axon guidance and me...

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Lee, Wei-Hsuan, Corgiat, Edwin, Rounds, J. Christopher, Shepherd, Zenyth, Corbett, Anita H., Moberg, Kenneth H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2020
Schlagworte:
Mutant Screen Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534439/
https://ncbi.nlm.nih.gov/pubmed/32817074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401637
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