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MyD88-mediated TLR signaling protects against acute rotavirus infection while inflammasome cytokines direct Ab response

Rotavirus (RV) infects small intestinal epithelial cells, inducing severe diarrhea in children, resulting in over 500,000 deaths annually. Relatively little is known about how innate immunity contains acute infection and drives adaptive immune responses that afford complete clearance of RV and prote...

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Библиографические подробности
Опубликовано в: :Innate Immun
Главные авторы: Uchiyama, Robin, Chassaing, Benoit, Zhang, Benyue, Gewirtz, Andrew T
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534410/
https://ncbi.nlm.nih.gov/pubmed/25213347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425914547435
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