UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma

CONTEXT: Sibiricose A5 (A5), sibiricose A6 (A6), 3,6′-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. OBJECTIVE: To compare the...

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Detalhes bibliográficos
Publicado no:Pharm Biol
Main Authors: Zhao, Xin, Xu, Baoxin, Wu, Peng, Zhao, Pan, Guo, Changchuan, Cui, Yueli, Zhang, Yanxue, Zhang, Xuelan, Li, Huifen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534330/
https://ncbi.nlm.nih.gov/pubmed/32956609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1818790
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