Evaluation of Cytotoxic Effect of Cholesterol End-Capped Poly(N-Isopropylacrylamide)s on Selected Normal and Neoplastic Cells

PURPOSE: Efficient intracellular delivery of a therapeutic compound is an important feature of smart drug delivery systems (SDDS). Modification of a carrier structure with a cell-penetrating ligand, ie, cholesterol moiety, is a strategy to improve cellular uptake. Cholesterol end-capped poly(N-isopr...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Misiak, Pawel, Niemirowicz-Laskowska, Katarzyna, Markiewicz, Karolina H, Misztalewska-Turkowicz, Iwona, Wielgat, Przemysław, Kurowska, Izabela, Siemiaszko, Gabriela, Destarac, Mathias, Car, Halina, Wilczewska, Agnieszka Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533236/
https://ncbi.nlm.nih.gov/pubmed/33061380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S262582
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